KEMS5380 Basics of NMR Spectroscopy (4 cr)

The aim of this course is to explore nuclear magnetic resonance as a phenomenon and to widely cover factors influencing on chemical shifts. Spin-spin coupling together with the 1D and 2D NMR experiments based on it as well as instrumental considerations, data collection, and processing are introduced at a theoretical level. Additionally, the course covers the basics of dynamic NMR spectroscopy.

• Construction and principles of the NMR spectrometer
• Collecting and processing of the FID
• Factors influencing on chemical shifts
• Spin-spin coupling
  
• The most common 1D and 2D NMR experiments
  
• Nuclear Overhauser effect (NOE)
• Relaxation and dynamic NMR spectroscopy

After completing the course the student

• Knows the basic principles and terms related to NMR spectroscopy.
  
• Understands the physical principles underlying the NMR phenomenon and realizes the possibilities of NMR spectroscopy in analyzing the structures of molecules.
• Is aware of the basic construction and principles of an NMR spectrometer.
  
• Is able to process the measured data with an appropriate way.
  
• Understands widely the factors influencing on chemical shifts.
  
• Is able to recognize and analyze coupling patterns.
  
• Understands the principles of the most common 1D and 2D NMR experiments and can apply them in structural analysis.
  
• Familiarizes her/himself with nuclear Overhauser effect and dynamic NMR spectroscopy.

Working life skills

• The student is able to plan and control the use of time related to duties and assignments, and is able to keep up with the agreed schedule.
  
• The student can combine and apply the knowledge learned during the course within a broader context.
• The student knows how to independently search for information and to evaluate its quality and reliability.
  
• The student is able to find answers and solutions to the given problems and exercises both orally and literally. The student is able to justify her/his answers.
• The student can discuss about NMR spectroscopy using the correct terminology.

The course replaces the previously lectured course KEMS536: Theoretical Basics of NMR Spectroscopy.

KEMS5390 or corresponding knowledge

• J.H. Simpson, Organic Structure Determination Using 2-D NMR Spectroscopy, 2nd Ed., Academic Press, 2012. Chapters 1-8.