KEMS5390 Practical NMR Spectroscopy (2 cr)

The course gives an introduction to the principles of nuclear magnetic resonance spectroscopy and its utilization in structural analysis.

• Basic concepts of NMR spectroscopy
  
• Chemical shift and factors influencing on it
• Spin-spin coupling
  
• Sample preparation
  
• Measurement and processing of the most common 1D and 2D NMR spectra
  
• Spectral interpretation exercises
  

After completing the course the student

• knows the basic principles and terms related to NMR spectroscopy.
  
• understands the physical principles underlying the NMR phenomenon and realizes the possibilities of NMR spectroscopy in analyzing the structures of molecules.
  
• knows factors influencing on chemical shifts.
  
• is able to analyze first-order coupling patterns.
  
• is aware of the principles on NMR sample preparation.
  
• knows how to choose the most reasonable NMR experiment(s) for each structural analysis.
  
• familiarizes her/himself with measuring NMR spectra.
  
• is able to analyze simple 1D and 2D NMR spectra.
  

Working life skills

• The student is able to plan and control the use of time related to duties and assignments, and is able to keep up with the agreed schedule.
  
• The student can combine and apply the knowledge learned during the course within a broader context.
• The student knows how to independently search for information and to evaluate its quality and reliability.
  
• The student is able to find answers and solutions to the given problems and exercises both orally and literally. The student is able to justify her/his answers.
• The student can discuss about NMR spectroscopy using the correct terminology.
  
• The student knows how to write a report about her/his work.
  

The course replaces the previously lectured course KEMS537: NMR Spectroscopy in Structural Elucidation.

The course will be lectured yearly in the 2. period.

Intermediate studies in Chemistry

• J.H. Simpson, Organic Structure Determination Using 2-D NMR Spectroscopy, 2nd Ed., Academic Press, 2012. Chapters 1, 2 (selected parts), 4-6, 9-10.